Home R & D Bio Novel Electrochemical Sensing of Dimetridazole Using a CN–ReS2 Composite

Novel Electrochemical Sensing of Dimetridazole Using a CN–ReS2 Composite

Novel Electrochemical Sensing of Dimetridazole Using a CN–ReS2 Composite

🔬 Researchers developed a novel electrochemical sensor for detecting dimetridazole (DMZ) using a composite of graphitic carbon nitride and rhenium disulfide (CN–ReS2). DMZ is an antimicrobial medication used in animal feed and human/veterinary medicine, posing risks to public health and the environment.

The CN–ReS2 composite was synthesized using a hydrothermal method, showing enhanced electrochemical activity for DMZ reduction, high stability, and sensitivity. The sensor demonstrated a promising limit of detection, rapid detection time, selectivity, and real-sample applications, suggesting its potential for sensitive and selective electrochemical sensing.


  • Composite: CN–ReS2
  • Synthesis: Hydrothermal method
  • DMZ: Antimicrobial medication used in animal and human/veterinary medicine
  • Sensor: Enhanced electrochemical activity, stability, sensitivity
  • Detection: Promising limit of detection, rapid response, selectivity
  • Applications: Real sample testing

The study presents a groundbreaking approach for detecting dimetridazole (DMZ), an antimicrobial compound used in various medical and veterinary applications, through an innovative electrochemical sensor. The sensor employs a composite material composed of graphitic carbon nitride (CN) and rhenium disulfide (ReS2). The synthesis of the CN–ReS2 composite involves a hydrothermal method, which creates flower-like structures of ReS2 on the surface of CN sheets. This novel composite material exhibits enhanced electrochemical activity, leading to efficient reduction of DMZ. The sensor has excellent performance characteristics. It is stable during operation and storage, sensitive, and can detect DMZ quickly. This makes it a promising tool for detecting DMZ in a wide range. Additionally, the sensor demonstrates excellent selectivity, repeatability, reproducibility, and flexibility, highlighting its potential for real-world applications.

The researchers emphasize the pressing environmental concerns associated with the increasing contamination of pharmaceuticals like DMZ, which poses risks to public health and the environment. They emphasize the need for reliable and rapid analytical tools to detect DMZ presence. The paper introduces the CN–ReS2 composite as a novel material for electrochemical sensing, highlighting its advantages over conventional detection methods. The researchers detail the synthesis process, characterization of the composite, and the performance of the developed electrochemical sensor. They emphasize the composite’s unique properties that contribute to enhanced sensor response and detection capabilities.

The development of the CN–ReS2 composite for electrochemical sensing of dimetridazole presents a significant advancement in analytical chemistry. This innovative approach addresses the challenges posed by pharmaceutical contamination, providing a sensitive and selective means to detect DMZ. The use of a composite material demonstrates the potential for tailoring material properties to achieve optimized sensor performance. The developed sensor has promising features, such as sensitivity, stability, rapid detection, and real sample applications. This suggests that it could be a practical tool for monitoring the presence of DMZ. This research contributes to the field of electrochemical sensing and underscores the importance of innovative solutions for environmental and public health concerns.

  • 💡 The increase in pharmaceutical contamination poses environmental and health threats.
  • 💡 Electrochemical sensing of dimetridazole (DMZ) is essential due to its adverse effects.
  • 💡 CN–ReS2 composite is used for the first time for electrochemical sensing.
  • 💡 Composite synthesis through one-step hydrothermal method with flower-like structures.
  • 💡 CN–ReS2-3 shows enhanced electrochemical response for DMZ reduction.
  • 💡 Promising limit of detection (LOD) of 19.8 nM, rapid detection (within 5 s).
  • 💡 Composite exhibits selectivity, storage stability, repeatability, and flexibility.
  • 🔬 Dimetridazole (DMZ) is used as an antimicrobial medication in animal feed and human/veterinary medicine.
  • 🔬 The CN–ReS2 composite was synthesized using a one-step hydrothermal method.
  • 🔬 CN–ReS2 composite exhibited enhanced electrochemical activity for DMZ reduction.
  • 🔬 3% ReS2 (CN–ReS2-3) showed the best electrochemical response.
  • 🔬 Developed sensor displayed a LOD of 19.8 nM and sensitivity of 0.246 μA nM−1 cm−2.
  • 🔬 Composite also showed rapid detection, selectivity, stability, repeatability, and flexibility.

Unveiling the capability of graphitic carbon nitride–rhenium disulfide nanocomposite as an electrochemical sensing platform for the detection of dimetridazole from human serum samples

  • M. Mufeeda, Pushpalatha V. Vaishag, Menon Ankitha and P. Abdul Rasheed
  • Environmental and health threats from pharmaceutical contamination.
  • CN–ReS2 composite for electrochemical DMZ sensing.
  • One-step hydrothermal synthesis with flower-like structures.
  • CN–ReS2-3 composition shows enhanced response.
  • Promising detection sensitivity, rapidity, and versatility.


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